Peptide Database

Peptide NamepTnI

Function Ontology

Anticancer

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC157H264N50O42S3

DescriptionStandard

        EDMNQKLFDLRGKFKRPPLRRVRMSADAML
    

Molecular Weight3620.28 Da

Isoelectric Point (pI)10.88

Net Charge (pH 7.0)3.84

Net Charge (pH 7.4) 3.66

Charge Density (pH 7.0) 0.1279

GRAVY Index-0.84

Hydrophobic Moment 0.69

Boman Index-0.36

Instability Index71.64

Aliphatic Index 68.33

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1532.81

LogP -13.15

H-bond Donors 54.0

H-bond Acceptors 49.0

Rotatable Bonds 126.0

Heavy Atoms 252.0

Ring Count 4.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431870 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-angiogenic; Anticancer

Targetmouse model of CAPAN-1 pancreatic cancer liver metastasis

Activity5.5 vs 11.1 liver/body weight ratio

Methodin vivo pancreatic cancer metastasis assay

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