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MYP_010491
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Basic Information
pTnI
Anticancer
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
30 amino acids
C157H264N50O42S3
Standard
Sequence
EDMNQKLFDLRGKFKRPPLRRVRMSADAML
Physicochemical Analysis
3620.28 Da
10.88
3.84
3.66
0.1279
-0.84
0.69
-0.36
71.64
68.33
0.0667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1532.81
-13.15
54.0
49.0
126.0
252.0
4.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0402992 VERIFIED: NO
Provenance & Taxonomy
Troponin I [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID21470139 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21470139/
RECORD: Rec_0431866 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic; Anticancer
HUVEC (human umbilical vein endothelial cells)
1 pg/mL
endothelial cell tube formation inhibition
PaperTroponin I peptide (Glu94-Leu123), a cartilage-derived angiogenesis inhibitor: in vitro and in vivo effects on human endothelial cells and on pancreatic cancer PMID14675705
RECORD: Rec_0431867 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic; Anticancer
HUVEC (human umbilical vein endothelial cells)
3 μg/mL
endothelial cell division inhibition (96 h)
PaperTroponin I peptide (Glu94-Leu123), a cartilage-derived angiogenesis inhibitor: in vitro and in vivo effects on human endothelial cells and on pancreatic cancer PMID14675705
RECORD: Rec_0431868 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic; Anticancer
HUVEC (human umbilical vein endothelial cells)
ICAM-1 expression assay
PaperTroponin I peptide (Glu94-Leu123), a cartilage-derived angiogenesis inhibitor: in vitro and in vivo effects on human endothelial cells and on pancreatic cancer PMID14675705
RECORD: Rec_0431869 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic; Anticancer
CAPAN-1 pancreatic cancer cells
VEGF production assay
PaperTroponin I peptide (Glu94-Leu123), a cartilage-derived angiogenesis inhibitor: in vitro and in vivo effects on human endothelial cells and on pancreatic cancer PMID14675705
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