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MYP_010475
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Basic Information
Amyloid precursor protein derived peptide
—
Standard
5 amino acids
C25H47N11O9S
Standard
Sequence
RERMS
Physicochemical Analysis
677.77 Da
9.60
0.76
0.56
0.1526
-2.28
0.11
-1.07
95.88
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
361.05
-4.53
14.0
11.0
24.0
46.0
0.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0181614 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
RECORD: Rec_0431862 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cell growth-promoting; Trophic peptide
A-1 fibroblasts
fibroblast growth-promoting bioassay
PaperAmino acid sequence RERMS represents the active domain of amyloid beta/A4 protein precursor that promotes fibroblast growth PMID8491779
RECORD: Rec_0431863 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neurotrophic; Neurite outgrowth-promoting
B103 neuronal cells
neurite outgrowth assay
PaperPeptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension PMID8083748