Peptide Database

Peptide NameNon-toxic phospholiapse A2 (WaPLA2) (svPLA2) (Phosphatidylcholine 2-acylhydrolase) (EC 3.1.1.4)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC149H225N37O41S5

DescriptionStandard

        NLYQFKNMVQCVGTQLCVAYVKYGCYCGPG
    

Molecular Weight3350.93 Da

Isoelectric Point (pI)8.48

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.44

Charge Density (pH 7.0) 0.0571

GRAVY Index0.22

Hydrophobic Moment 0.48

Boman Index0.20

Instability Index-17.36

Aliphatic Index 68.00

Aromaticity 0.1667

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6210.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1267.07

LogP -11.08

H-bond Donors 46.0

H-bond Acceptors 48.0

Rotatable Bonds 105.0

Heavy Atoms 232.0

Ring Count 6.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0165403 VERIFIED: YES

Provenance & Taxonomy

OrganismWalterinnesia aegyptia [Animal]

FamilyPhospholipase A2; Group I subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-positive Hydrolase Cytolytic Cytotoxic Hemolytic

TargetF. solani (Gram-positive)

RECORD: Rec_0170593 VERIFIED: YES

Provenance & Taxonomy

OrganismWalterinnesia aegyptia [Animal]

FamilyPhospholipase A2; Group I subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-positive Hydrolase Cytolytic Cytotoxic Hemolytic

TargetP. digitatum

RECORD: Rec_0252633 VERIFIED: YES

Provenance & Taxonomy

OrganismWalterinnesia aegyptia [Animal]

FamilyPhospholipase A2; Group I subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-positive Hydrolase Cytolytic Cytotoxic Hemolytic

TargetB. cinerea

RECORD: Rec_0410773 VERIFIED: YES

Provenance & Taxonomy

OrganismWalterinnesia aegyptia [Animal]

FamilyPhospholipase A2; Group I subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-positive Hydrolase Cytolytic Cytotoxic Hemolytic

TargetA. niger