Peptide Database

Peptide NameGalanin message-associated peptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length60 amino acids

Chemical FormulaC292H475N75O96S

DescriptionStandard

        ELQLEVEERRPGSVDVPLPESNIVRTIMEFLSFLHLKEAGALDSLPGIPLATSSEDLEKS
    

Molecular Weight6604.41 Da

Isoelectric Point (pI)4.37

Net Charge (pH 7.0)-7.05

Net Charge (pH 7.4) -7.29

Charge Density (pH 7.0) -0.1175

GRAVY Index-0.14

Hydrophobic Moment 0.74

Boman Index0.04

Instability Index60.71

Aliphatic Index 108.83

Aromaticity 0.0333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2718.54

LogP -24.98

H-bond Donors 91.0

H-bond Acceptors 91.0

Rotatable Bonds 220.0

Heavy Atoms 464.0

Ring Count 8.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0123062 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyGalanin message-associated peptide

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other Mods53:Phosphoserine; 54:Phosphoserine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Myotropic Receptor modulation Feeding regulator

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0133827 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0372706 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyGalanin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsSer54 Phosphoserine

Bio-Activity Profile

Function

Neuropeptide Neuromodulator