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MYP_010390
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Binding / Molecular interaction ▸ Binding activity
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Lipoxygenase Inhibitory
Hemostasis ▸ Anticoagulant activity
Hemostasis ▸ Antithrombotic activity
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Therapeutic / Biomedical activity ▸ Regenerative medicine ▸ Bone metabolism ▸ Osteoanabolic activity
Standard
7 amino acids
C38H59N11O10
Standard
Sequence
AVPYPQR
Physicochemical Analysis
829.94 Da
8.79
0.79
0.61
0.1136
-0.93
0.50
-0.17
81.23
55.71
0.1429
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
345.56
-2.53
11.0
11.0
21.0
59.0
3.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0290374 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant ABTS radical scavenging
Caco-2 cells
PaperMilk-derived bioactive peptides exhibit antioxidant activity through the Keap1-Nrf2 signaling pathway | Tonolo, F. et al. | DOI: 10.1016/j.jff.2019.103696 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0301124 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli; Bacillus subtilis
150 μg/mL
MIC
PaperIdentification of novel antibacterial peptides isolated from a commercially available casein hydrolysate by autofocusing technique | Elbarbary, H. et al. | DOI: 10.1002/biof.1023 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0312816 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
ACE-inhibitory peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
274 μM
IC50
PaperAngiotensin I Converting Enzyme Inhibitory Peptides Derived from Bovine Milk Proteins (
RECORD: Rec_0318016 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Cytomodulatory
RECORD: Rec_0320527 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-inflammatory Lipoxygenase Inhibitory
Lipoxygenase
PaperRival S. G., Fornaroli S., Boeriu C. G., Wichers H. J.. Caseins and casein hydrolysates. 1. Lipoxygenase inhibitory properties. J. Agric. Food Chem., 49 (2001), 287-294.
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