Peptide Database

Peptide NameC-terminal fragment of Porcine Endothelin-1 (Porcine CTF)

Function Ontology

Vasoconstricting peptide

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC83H135N25O27

DescriptionStandard

        VNTPERVVPYGLGSPSRS
    

Molecular Weight1915.11 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)0.74

Net Charge (pH 7.4) 0.52

Charge Density (pH 7.0) 0.0409

GRAVY Index-0.53

Hydrophobic Moment 0.50

Boman Index-0.07

Instability Index90.59

Aliphatic Index 70.00

Aromaticity 0.0556

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 836.99

LogP -10.99

H-bond Donors 29.0

H-bond Acceptors 28.0

Rotatable Bonds 56.0

Heavy Atoms 135.0

Ring Count 4.0

Amide Bonds 18.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0240293 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyEndothelin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Vasoconstricting peptide

MethodRadioimmunoassay and RP-HPLC

Half-LifePurified ET-1 protein sample, in vitro; 2820 s