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MYP_010375
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Basic Information
Temporin L [F1L,V2L,F5L,F8L,I12L]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C75H129N19O16
Standard
Sequence
LLQWLSKLLGRLL
Physicochemical Analysis
1552.94 Da
11.00
1.76
1.55
0.1353
0.97
0.66
0.28
37.27
210.00
0.0769
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
579.55
-0.46
21.0
18.0
53.0
110.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0158826 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
8407.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
6 μM
Hemolysis
PaperMangoni ML, Carotenuto A, Auriemma L, et al. Structure-activity relationship, conformational and biological studies of temporin L analogues. J Med Chem. 2011 Mar 10;54(5):1298-1307. doi:10.1021/jm1012853. PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0163836 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus epidermidis ATCC 12228
1.5 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0169313 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 15692
12 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0175682 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
24 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0181877 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
3 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
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