Peptide Database

Peptide NameSaha-CATH4

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC217H345N67O58

DescriptionStandard

        KREDFLDQIIRDFRNFIYQKYRRLRDEFRKLRDILSG
    

Molecular Weight4820.47 Da

Isoelectric Point (pI)10.14

Net Charge (pH 7.0)3.77

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1018

GRAVY Index-1.14

Hydrophobic Moment 0.89

Boman Index-0.48

Instability Index43.18

Aliphatic Index 84.32

Aromaticity 0.1622

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2135.24

LogP -16.29

H-bond Donors 78.0

H-bond Acceptors 62.0

Rotatable Bonds 170.0

Heavy Atoms 342.0

Ring Count 6.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0404015 VERIFIED: YES

Provenance & Taxonomy

OrganismSarcophilus harrisii [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetS. pneumoniae ATCC 49619

Activity64 μg/mL

MethodMIC

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