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MYP_010364
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Basic Information
Saha-CATH4
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
37 amino acids
C217H345N67O58
Standard
Sequence
KREDFLDQIIRDFRNFIYQKYRRLRDEFRKLRDILSG
Physicochemical Analysis
4820.47 Da
10.14
3.77
3.55
0.1018
-1.14
0.89
-0.48
43.18
84.32
0.1622
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2135.24
-16.29
78.0
62.0
170.0
342.0
6.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0166819 VERIFIED: YES
Provenance & Taxonomy
Sarcophilus harrisii [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli
>64 μg/mL
MIC
PMID27725697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27725697/
RECORD: Rec_0176046 VERIFIED: YES
Provenance & Taxonomy
Sarcophilus harrisii [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida parapsilosis ATCC 22019
>64 μg/mL
MIC
PMID27725697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27725697/
RECORD: Rec_0192487 VERIFIED: YES
Provenance & Taxonomy
Sarcophilus harrisii [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
DFT1 1426 cells
50 % viability reduction
cell viability assay (alamarBlue)
PaperTasmanian devil cathelicidins exhibit anticancer activity against Devil Facial Tumour Disease (DFTD) cells. DOI:10.1038/s41598-023-39901-0
RECORD: Rec_0207715 VERIFIED: NO
Provenance & Taxonomy
Sarcophilus harrisii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 27725697 PMID27725697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27725697/
RECORD: Rec_0215554 VERIFIED: YES
Provenance & Taxonomy
Sarcophilus harrisii [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Streptococcus oralis/mitis group
>64 μg/mL
MIC
PMID27725697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27725697/
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