Peptide Database

Peptide Namealpha-2 gliadin (p219-p242; E229) AJ133612

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC113H167N35O42

DescriptionStandard

        QQPQQQYPSGEGSFQPSQQNPQAQ
    

Molecular Weight2687.74 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0516

GRAVY Index-2.01

Hydrophobic Moment 0.22

Boman Index-0.29

Instability Index95.52

Aliphatic Index 4.17

Aromaticity 0.0833

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1289.67

LogP -20.58

H-bond Donors 37.0

H-bond Acceptors 41.0

Rotatable Bonds 85.0

Heavy Atoms 190.0

Ring Count 6.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078334 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E229

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman HLA-DQ8-positive coeliac mucosa

MethodOrgan culture