Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC170H263N49O51S6

DescriptionStandard

        DHYNCVRSGGQCLYSACPIYTKIEGTCYHGKAKCCK
    

Molecular Weight4001.59 Da

Isoelectric Point (pI)8.62

Net Charge (pH 7.0)2.87

Net Charge (pH 7.4) 2.47

Charge Density (pH 7.0) 0.0798

GRAVY Index-0.45

Hydrophobic Moment 0.56

Boman Index-0.06

Instability Index58.80

Aliphatic Index 46.11

Aromaticity 0.1111

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1618.99

LogP -18.46

H-bond Donors 63.0

H-bond Acceptors 62.0

Rotatable Bonds 129.0

Heavy Atoms 276.0

Ring Count 7.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0313871 VERIFIED: YES

Provenance & Taxonomy

OrganismColobus angolensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)