Peptide Database

Peptide NameInterferon-induced transmembrane protein 2

Function Ontology

Antiviral

Antiviral ▸ Anti-Filovirus ▸ Anti-Ebola virus

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC710H1103N181O207S8

DescriptionStandard

        MSHNSQAFLSTNAGLPPSYETIKEEYGVTELGEPSNSAVVRTTVINMPREVSVPDHVVWSLFNTLFFNACCLGFVAYAYSVKSRDRKMVGDVVGAQAYASTAKCLNISSLIFSILMVIICIIIFSTTSVVVFQSFAQRTPHSGF
    

Molecular Weight15742.96 Da

Isoelectric Point (pI)6.81

Net Charge (pH 7.0)-0.27

Net Charge (pH 7.4) -0.72

Charge Density (pH 7.0) -0.0019

GRAVY Index0.40

Hydrophobic Moment 0.49

Boman Index0.21

Instability Index44.05

Aliphatic Index 93.33

Aromaticity 0.1111

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13200.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6164.57

LogP -61.75

H-bond Donors 219.0

H-bond Acceptors 218.0

Rotatable Bonds 504.0

Heavy Atoms 1106.0

Ring Count 26.0

Amide Bonds 154.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0174813 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyIFITM

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Ser19

Bio-Activity Profile

Function

Antiviral Entry inhibitor Anti-EBOV

TargetEbola virus(EBOV)

RECORD: Rec_0177127 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyIFITM

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Ser19

Bio-Activity Profile

Function

Antiviral Anti-IAV

TargetInfluenza A virus(IAV)

RECORD: Rec_0410482 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyIFITM

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Ser19

Bio-Activity Profile

Function

Antiviral Entry inhibitor Replication inhibitor

TargetSARS-CoV