MYP_010254
Pituitary adenylate cyclase-activating polypeptide-27
Cardiovascular
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Vascular tone modulation
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Vasoactive peptide
Cardiovascular
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Vascular tone modulation
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Vasodilatory activity
Delivery / Targeting
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Barrier transport
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Blood-brain barrier shuttle
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Blood-Brain Barrier
Delivery / Targeting
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Drug delivery vehicle
Enzyme modulation
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Enzyme inhibition
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ACE inhibition
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ACE inhibitory
Hormonal / Endocrine
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Hormone peptide
Immunology
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Chemokine signaling
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Chemokine-like peptide
Neurological / Signaling
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Neuromodulation
Neurological / Signaling
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Neuropeptide activity
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Neuropeptide
Neurological / Signaling
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Neuropeptide activity
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Neuropeptide signaling
Regulatory peptide
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Biological modulation
Regulatory peptide
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Biological regulation
Regulatory peptide
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Cell-cell communication
Reproductive biology
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Reproductive modulation
Standard
27 amino acids
C142H223N39O40S
Standard
HSDGIFTDSYSRYRKQMAVKKYLAAVL
3148.59 Da
9.70
2.84
2.58
0.1053
-0.41
0.44
-0.10
23.96
75.93
0.1481
4470.00
4470.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1309.76
-11.56
48.0
45.0
105.0
222.0
5.0
27.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0227993
VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Pituitary adenylate cyclase-activating polypeptide
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone
Endocrine
Neuropeptide
Neuromodulator
Metabolic regulation
Physiological regulation
Growth regulation
Development regulation
Receptor modulation
ACE inhibitory
Experimental: 39±4 minutes; /2340 seconds; Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
RECORD: Rec_0250672
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
PACAP
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Hexanoylation
Amidation
Bio-Activity Profile
Neuroprotective
0.0106±0.0024 μM
IC50
DPP IV, in vitro; >14400 s
RECORD: Rec_0251437
VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Pituitary adenylate cyclase-activating polypeptide
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone
Endocrine
Neuropeptide
Neuromodulator
Vasoactive
Vasodilator
Metabolic regulation
Physiological regulation
Growth regulation
Development regulation
Receptor modulation
ACE inhibitory
its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells
Experimental: 39±4 minutes; /2340 seconds; Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
RECORD: Rec_0266372
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
PACAP
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Neuroprotective
0.0056±0.0013 μM
IC50
Human plasma, in vitro; >7200 s
RECORD: Rec_0271254
VERIFIED: NO
Provenance & Taxonomy
Ovis aries [Animal]; Sus scrofa [Animal]; Helix pomatia [Animal]
9940, 9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Enzyme Activator
Showing 5 records on this page · Page 6 of 9