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MYP_010248
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Basic Information
Unnamed
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
25 amino acids
C99H169N41O34S7
Standard
Sequence
CQGRGASCRKTMYNCCSGSCNRGRC
Physicochemical Analysis
2702.11 Da
9.22
4.70
4.41
0.1879
-0.79
0.32
-0.38
30.80
4.00
0.0400
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1265.76
-22.58
53.0
46.0
91.0
181.0
1.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0150278 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Cytotoxic
PaperConoServer: updated content, knowledge, and discovery tools in the conopeptide database PMID22058133 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22058133/
RECORD: Rec_0204175 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Miscellaneous
PaperConoServer: updated content, knowledge, and discovery tools in the conopeptide database PMID22058133 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22058133/
RECORD: Rec_0278441 VERIFIED: YES
Provenance & Taxonomy
Conus magus [Animal]
Conotoxin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
1-16; 8-20; 15-25
Bio-Activity Profile
Toxin Calcium channel blocker Q-type calcium-channel inhibitor
bovine adrenal medullary membrane [125I] omega-conotoxin MVIIC binding sites
~80 nM
IC50 (radioligand displacement binding assay)
PaperAnalogies and differences between omega-conotoxins MVIIC and MVIID: binding sites and functions in bovine chromaffin cells PMID9359903
RECORD: Rec_0431828 VERIFIED: YES
Provenance & Taxonomy
Conus magus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
1-16; 8-20; 15-25
Bio-Activity Profile
Toxin Calcium channel blocker Q-type calcium-channel inhibitor
bovine adrenal chromaffin cells
70 %
K+-evoked 45Ca2+ uptake inhibition assay
PaperAnalogies and differences between omega-conotoxins MVIIC and MVIID: binding sites and functions in bovine chromaffin cells PMID9359903
RECORD: Rec_0431829 VERIFIED: YES
Provenance & Taxonomy
Conus magus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
1-16; 8-20; 15-25
Bio-Activity Profile
Toxin Calcium channel blocker Q-type calcium-channel inhibitor
bovine adrenal chromaffin cells
70 %
K+-evoked catecholamine secretion inhibition assay
PaperAnalogies and differences between omega-conotoxins MVIIC and MVIID: binding sites and functions in bovine chromaffin cells PMID9359903