MYP_010212
Basic Information
Huwentoxin-V mutant, mHuwentoxin-V
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Toxic
Venom / Toxin General toxin Toxin
Standard
33 amino acids
C164H229N47O52S6
Standard
Sequence
ECRWYLGGCSQDGDCCKHLQCHSNYEWCVWDGT
Physicochemical Analysis
3883.25 Da
4.80
-3.05
-3.41
-0.0923
-0.76
0.34
-0.06
61.56
32.42
0.1515
19480.00
19855.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1604.09
-16.92
62.0
57.0
121.0
269.0
10.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0149061 VERIFIED: YES
Provenance & Taxonomy
Selenocosmia huwena [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported, sites unresolved
Bio-Activity Profile
Toxin Insecticidal toxin Experimentally inactive mutant
locusts; cockroaches
insect toxicity assay
RECORD: Rec_0311014 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Cytotoxic
RECORD: Rec_0431825 VERIFIED: YES
Provenance & Taxonomy
Selenocosmia huwena [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported, sites unresolved
Bio-Activity Profile
Toxin Experimentally inactive mutant
mice
in vivo toxicity assay (intraperitoneal/intracerebroventricular administration)
RECORD: Rec_0431826 VERIFIED: YES
Provenance & Taxonomy
Selenocosmia huwena [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported, sites unresolved
Bio-Activity Profile
Toxin Experimentally inactive mutant
isolated mouse phrenic nerve-diaphragm preparation
neuromuscular transmission assay