Peptide Database

Peptide NameLysozyme 1 (EC 3.2.1.17) (1;4-beta-N-acetylmuramidase 1) (Invertebrate-type lysozyme 1) (cv-lysozyme 1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC827H1289N273O258S25

DescriptionStandard

        MNGLILFCAVVFATAVCTYGSDAPCLRAGGRCQHDSITCSGRYRTGLCSGGVRRRCCVPSSSNSGSFSTGMVSQQCLRCICNVESGCRPIGCHWDVNSDSCGYFQIKRAYWIDCGSPGGDWQTCANNLACSSRCVQAYMARYHRRSGCSNSCESFARIHNGGPRGCRNSNTEGYWRRVQAQGCN
    

Molecular Weight19985.38 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)10.64

Net Charge (pH 7.4) 9.88

Charge Density (pH 7.0) 0.0578

GRAVY Index-0.32

Hydrophobic Moment 0.80

Boman Index-0.07

Instability Index57.59

Aliphatic Index 49.84

Aromaticity 0.0870

Extinction Coeff. Reduced 32430.00

Extinction Coeff. Oxidized 33805.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8607.36

LogP -121.91

H-bond Donors 332.0

H-bond Acceptors 298.0

Rotatable Bonds 645.0

Heavy Atoms 1383.0

Ring Count 29.0

Amide Bonds 202.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006008 VERIFIED: YES

Provenance & Taxonomy

OrganismCrassostrea virginica [Animal]

FamilyGlycosyl hydrolase 22; Type-I lysozyme subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriolytic enzyme Anti-Gram-negative Anti-Gram-positive Glycosidase Hydrolase Non-hemolytic

TargetEnterococcus (Gram-positive)

RECORD: Rec_0106839 VERIFIED: YES

Provenance & Taxonomy

OrganismCrassostrea virginica [Animal]

FamilyGlycosyl hydrolase 22; Type-I lysozyme subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriolytic enzyme Anti-Gram-negative Anti-Gram-positive Glycosidase Hydrolase Non-hemolytic

TargetMicrococcus luteus (Gram-negative)

RECORD: Rec_0169888 VERIFIED: YES

Provenance & Taxonomy

OrganismCrassostrea virginica [Animal]

FamilyGlycosyl hydrolase 22; Type-I lysozyme subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriolytic enzyme Anti-Gram-negative Anti-Gram-positive Glycosidase Hydrolase Non-hemolytic

TargetL. garvieae (Gram-positive)