Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length244 amino acids

Chemical FormulaC1256H1907N285O357S9

DescriptionStandard

        IDHLAKVDYSSNSLPAVFRPFIDLDLKGIVYPAGNYSGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEEVKSGKLFHLFFLFFLQTCSYFNISLEIFGSIIPEVAKYSVTPCPVMLKLMATEIPIISLEKDSFTVEIQGSMEAFAVLPDSTTQSLFTMNIAANTSIALNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENVLSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight26999.86 Da

Isoelectric Point (pI)4.69

Net Charge (pH 7.0)-8.99

Net Charge (pH 7.4) -9.44

Charge Density (pH 7.0) -0.0368

GRAVY Index0.41

Hydrophobic Moment 0.60

Boman Index0.27

Instability Index41.27

Aliphatic Index 100.37

Aromaticity 0.1393

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239124 VERIFIED: NO

Provenance & Taxonomy

OrganismSula dactylatra [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria