Peptide Database

Peptide NameSLAY-screened peptide P4215

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC102H157N23O34S

DescriptionStandard

        TTLDPLLPDFVPTTCDNSGKF
    

Molecular Weight2281.54 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.61

Net Charge (pH 7.4) -2.82

Charge Density (pH 7.0) -0.1243

GRAVY Index-0.14

Hydrophobic Moment 0.38

Boman Index0.11

Instability Index25.81

Aliphatic Index 69.52

Aromaticity 0.0952

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 901.11

LogP -9.60

H-bond Donors 30.0

H-bond Acceptors 33.0

Rotatable Bonds 67.0

Heavy Atoms 160.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0203264 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/