Peptide Database

Peptide NameNeuromedin-U-25

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC128H199N37O36

DescriptionStandard

        LKPDEELQGPGGVLSRGYFVFRPRN
    

Molecular Weight2832.18 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0306

GRAVY Index-0.72

Hydrophobic Moment 0.42

Boman Index-0.12

Instability Index41.72

Aliphatic Index 70.00

Aromaticity 0.1200

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1185.61

LogP -10.78

H-bond Donors 40.0

H-bond Acceptors 37.0

Rotatable Bonds 90.0

Heavy Atoms 201.0

Ring Count 6.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106872 VERIFIED: YES

Provenance & Taxonomy

OrganismRana temporaria [Animal]

FamilyNeuromedin-U

Tax ID8407

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasoconstrictor Myotropic

Half-LifeMammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0422104 VERIFIED: NO