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MYP_010164
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Basic Information
C12-Anoplin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
10 amino acids
C54H103N15O12
Standard
Sequence
GLLKRIKTLL
Physicochemical Analysis
1154.49 Da
11.17
2.76
2.55
0.2758
0.63
0.59
0.05
24.62
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
459.39
-1.47
17.0
15.0
42.0
81.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0397436 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
C10
Amidation
Bio-Activity Profile
Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
PMID32649983 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32649983/
RECORD: Rec_0400206 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
C12
Amidation
Bio-Activity Profile
Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 23857
PMID32649983 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32649983/
RECORD: Rec_0405321 VERIFIED: YES
Provenance & Taxonomy
Anoplius samariensis [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
bacillus subtilis
32 μg/mL
MIC
PaperPubMed PMID: 29614317 | PubMed PMID: 25316570 | PubMed PMID: 27862650 PMID29614317;25316570;27862650 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29614317/
RECORD: Rec_0410127 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Solitary wasp [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
PaperAnoplin, a novel antimicrobial peptide from the venom of the solitary wasp Anoplius samariensis.
RECORD: Rec_0414531 VERIFIED: YES
Provenance & Taxonomy
Anoplius samariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Refer Pubmed ID: [E. coli K12 MG1655 (
16 μM
MIC
PMID11738089;34180670;31676352;34966367 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11738089/
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