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MYP_010164
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Basic Information
C12-Anoplin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
10 amino acids
C54H103N15O12
Standard
Sequence
GLLKRIKTLL
Physicochemical Analysis
1154.49 Da
11.17
2.76
2.55
0.2758
0.63
0.59
0.05
24.62
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
459.39
-1.47
17.0
15.0
42.0
81.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0037993 VERIFIED: YES
Provenance & Taxonomy
Anoplius samariensis [Animal]
Anoplin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperBiochim Biophys Acta 2001;1550(1): 70-80 | http://www.ncbi.nlm.nih.gov/pubmed/11738089 PMID11738089 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11738089/
RECORD: Rec_0038734 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 70.0%, E 0.0%, T 10.0%, C 20.0% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic Anti-Gram-positive Anti-Gram-negative Mast cell degranulation
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0040133 VERIFIED: YES
Provenance & Taxonomy
Anoplius samariensis [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus subtilis DELTA
300 μg/mL
MIC
PaperPubMed PMID: 29614317 | PubMed PMID: 25316570 | PubMed PMID: 27862650 PMID29614317;25316570;27862650 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29614317/
RECORD: Rec_0042750 VERIFIED: YES
Provenance & Taxonomy
Anoplius samariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
C16
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 10231
6.5 μg/mL
MIC
PMID29614317 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29614317/
RECORD: Rec_0044933 VERIFIED: YES
Provenance & Taxonomy
Anoplius samariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
[Refer PubMed ID - 31676352 (C terminal: NH2): Escherichia coli ATCC 25922 [
8 μM
MIC
PMID11738089;34180670;31676352;34966367 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11738089/
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