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MYP_010164
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Basic Information
C12-Anoplin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
10 amino acids
C54H103N15O12
Standard
Sequence
GLLKRIKTLL
Physicochemical Analysis
1154.49 Da
11.17
2.76
2.55
0.2758
0.63
0.59
0.05
24.62
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
459.39
-1.47
17.0
15.0
42.0
81.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0291652 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Bio-Activity Profile
Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27858
PMID32649983 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32649983/
RECORD: Rec_0293677 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
C14
Amidation
Bio-Activity Profile
Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
PMID32649983 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32649983/
RECORD: Rec_0293918 VERIFIED: YES
Provenance & Taxonomy
Anoplius samariensis [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli ATCC 25922
13 μg/mL
MIC
PaperPubMed PMID: 29614317 | PubMed PMID: 25316570 | PubMed PMID: 27862650 PMID29614317;25316570;27862650 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29614317/
RECORD: Rec_0299166 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
128 μM
MIC
PMID25530580;32649983 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25530580/
RECORD: Rec_0307556 VERIFIED: YES
Provenance & Taxonomy
Anoplius samariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
No hemolytic activity against human erthyrocytes
256 μM
Hemolysis
PMID11738089;34180670;31676352;34966367 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11738089/
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