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MYP_010164
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Basic Information
C12-Anoplin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
10 amino acids
C54H103N15O12
Standard
Sequence
GLLKRIKTLL
Physicochemical Analysis
1154.49 Da
11.17
2.76
2.55
0.2758
0.63
0.59
0.05
24.62
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
459.39
-1.47
17.0
15.0
42.0
81.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0224816 VERIFIED: YES
Provenance & Taxonomy
Anoplius samariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Refer Pubmed ID: [E. coli K12 MG1655 (
64 μM
MIC
PMID11738089;34180670;31676352;34966367 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11738089/
RECORD: Rec_0237572 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Bio-Activity Profile
Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27862
PMID32649983 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32649983/
RECORD: Rec_0237609 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
C12
Amidation
Bio-Activity Profile
Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
PMID32649983 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32649983/
RECORD: Rec_0238813 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
C14
Amidation
Bio-Activity Profile
Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27878
PMID32649983 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32649983/
RECORD: Rec_0239006 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Anoplin
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Fatty acylation
Amidation
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial Antifungal
Mycobacterium smegmatis mc2 157
200 μg/mL
MIC
PMID27862650 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27862650/
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