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MYP_010164
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Basic Information
C12-Anoplin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
10 amino acids
C54H103N15O12
Standard
Sequence
GLLKRIKTLL
Physicochemical Analysis
1154.49 Da
11.17
2.76
2.55
0.2758
0.63
0.59
0.05
24.62
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
459.39
-1.47
17.0
15.0
42.0
81.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0175591 VERIFIED: YES
Provenance & Taxonomy
Anoplius samariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
[Refer PubMed ID 34180670: S. aureus ATCC 25923 (
16 μM
MIC
PMID11738089;34180670;31676352;34966367 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11738089/
RECORD: Rec_0177175 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
C8
Amidation
Bio-Activity Profile
Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27880
PMID32649983 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32649983/
RECORD: Rec_0178112 VERIFIED: YES
Provenance & Taxonomy
Anoplius samariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Gram-negative Anti-Gram-positive Hemolytic
Gram Negative Bacteria and Gram Positive Bacteria
PMID11006592;11738089;15635634;17994639;24472551;27096870;25530580 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11006592/
RECORD: Rec_0183717 VERIFIED: YES
Provenance & Taxonomy
Anoplius samariensis [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
mice red blood cells
PaperPubMed PMID: 29614317 | PubMed PMID: 25316570 | PubMed PMID: 27862650 PMID29614317;25316570;27862650 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29614317/
RECORD: Rec_0187296 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
C12
Amidation
Bio-Activity Profile
Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27876
PMID32649983 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32649983/
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