Peptide Database

Peptide NameBeta-defensin 33

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC309H520N94O79S9

DescriptionStandard

        MRLLFLLFILLVCLAQTTSGRKRNSKFRPCEKMGGICKSQKTHGCSILPAECKSRYKHCCRL
    

Molecular Weight7104.60 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)10.60

Net Charge (pH 7.4) 10.17

Charge Density (pH 7.0) 0.1710

GRAVY Index-0.08

Hydrophobic Moment 0.50

Boman Index-0.10

Instability Index49.58

Aliphatic Index 83.39

Aromaticity 0.0645

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2817.68

LogP -26.90

H-bond Donors 109.0

H-bond Acceptors 101.0

Rotatable Bonds 245.0

Heavy Atoms 491.0

Ring Count 8.0

Amide Bonds 64.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0310237 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q30KN3/entry; https://bblserver.org.in/ampdb/