‹ ›
MYP_010133
← PREVIOUS NEXT → BACK
Basic Information
R102
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Standard
25 amino acids
C124H202N36O41S
Standard
Sequence
SDHSESIQKKFQLMKEHVNKIGVDS
Physicochemical Analysis
2885.21 Da
6.67
-0.36
-0.68
-0.0145
-0.97
0.55
-0.20
29.76
70.00
0.0400
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1282.55
-14.39
43.0
44.0
104.0
202.0
3.0
27.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0039257 VERIFIED: YES
Provenance & Taxonomy
Avian leukosis virus [Virus]
Heptad repeat peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor Fusion inhibitor
Avian sarcoma and leukosis virus A (Virus entry); QT6
5 μM
Cell-fusion assay
PaperHeptad repeat 2-based peptides inhibit avian sarcoma and leukosis virus subgroup a infection and identify a fusion intermediate. | Netter RC, Amberg SM, Balliet JW, Biscone MJ, Vermeulen A, Earp LJ, White JM, Bates P. | J Virol. 2004 | PMID:15564453 PMID15564453 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15564453/
RECORD: Rec_0133725 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses (https://pubmed.ncbi.nlm.nih.gov/24285301/) PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/