Peptide Database

Peptide NameEsculentin-2Vb (esc2Vb) (Esculentin 2VEb)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC377H636N96O110S7

DescriptionStandard

        MFTMKKSLLLLFFLGTISLSLCEEERGADEEEGDGEKLMKRGLFSILKGVGKIAIKGLGKNLGKMGLDLVSCKISKEC
    

Molecular Weight8498.11 Da

Isoelectric Point (pI)8.49

Net Charge (pH 7.0)1.49

Net Charge (pH 7.4) 1.19

Charge Density (pH 7.0) 0.0190

GRAVY Index0.12

Hydrophobic Moment 0.64

Boman Index0.08

Instability Index28.85

Aliphatic Index 105.00

Aromaticity 0.0513

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3329.27

LogP -26.45

H-bond Donors 119.0

H-bond Acceptors 119.0

Rotatable Bonds 310.0

Heavy Atoms 590.0

Ring Count 4.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010371 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana versabilis [Animal]

FamilyFrog skin active peptide (FSAP); Esculentin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Non-hemolytic