Peptide Database

Peptide Namebeta-Defensin 8

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC164H264N52O46S6

DescriptionStandard

        NEPVSCYRNGGICQYRCIGLRHKIGTCGSPFKCCK
    

Molecular Weight3892.56 Da

Isoelectric Point (pI)9.13

Net Charge (pH 7.0)4.79

Net Charge (pH 7.4) 4.44

Charge Density (pH 7.0) 0.1367

GRAVY Index-0.38

Hydrophobic Moment 0.39

Boman Index-0.11

Instability Index43.08

Aliphatic Index 52.86

Aromaticity 0.0857

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1595.30

LogP -19.00

H-bond Donors 62.0

H-bond Acceptors 58.0

Rotatable Bonds 127.0

Heavy Atoms 268.0

Ring Count 6.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0071103 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-33; 13-27; 17-34

Bio-Activity Profile

Function

Antimicrobial Antibacterial