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MYP_010025
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Basic Information
Gallinacin-10 (Gal-10) (Beta-defensin 10) (Gallinacin-8) (Gal-8)
Antimicrobial
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
68 amino acids
C319H502N84O85S8
Standard
Sequence
MKILCLLFAVLLFLFQAAPGSADPLFPDTVACRTQGNFCRAGACPPTFTISGQCHGGLLNCCAKIPAQ
Physicochemical Analysis
7130.43 Da
8.24
1.52
1.15
0.0223
0.65
0.56
0.28
34.66
90.59
0.0882
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2619.32
-24.51
93.0
96.0
221.0
496.0
13.0
73.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0431803 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibacterial Defensin
Salmonella typhimurium ATCC 14028
100±3.46 μg/mL
MBC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID25941665
RECORD: Rec_0431804 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibacterial Defensin
Klebsiella pneumoniae ATCC 700603
25±0.0 μg/mL
MIC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID25941665
RECORD: Rec_0431805 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibacterial Defensin
Klebsiella pneumoniae ATCC 700603
100±1.73 μg/mL
MBC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID25941665
RECORD: Rec_0431806 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibacterial Defensin
Shigella sonnei ATCC 25931
50±1.73 μg/mL
MIC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID25941665
RECORD: Rec_0431807 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibacterial Defensin
Shigella sonnei ATCC 25931
100±0.58 μg/mL
MBC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID25941665
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