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MYP_010025
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Basic Information
Gallinacin-10 (Gal-10) (Beta-defensin 10) (Gallinacin-8) (Gal-8)
Antimicrobial
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
68 amino acids
C319H502N84O85S8
Standard
Sequence
MKILCLLFAVLLFLFQAAPGSADPLFPDTVACRTQGNFCRAGACPPTFTISGQCHGGLLNCCAKIPAQ
Physicochemical Analysis
7130.43 Da
8.24
1.52
1.15
0.0223
0.65
0.56
0.28
34.66
90.59
0.0882
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2619.32
-24.51
93.0
96.0
221.0
496.0
13.0
73.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0431798 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibacterial Defensin
Escherichia coli ATCC 25922
50±1.73 μg/mL
MIC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID25941665
RECORD: Rec_0431799 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibacterial Defensin
Escherichia coli ATCC 25922
100±3.46 μg/mL
MBC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID25941665
RECORD: Rec_0431800 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibacterial Defensin
Pseudomonas aeruginosa ATCC 27853
50±0.0 μg/mL
MIC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID25941665
RECORD: Rec_0431801 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibacterial Defensin
Pseudomonas aeruginosa ATCC 27853
200±3.46 μg/mL
MBC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID25941665
RECORD: Rec_0431802 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibacterial Defensin
Salmonella typhimurium ATCC 14028
50±0.58 μg/mL
MIC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID25941665
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