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MYP_010025
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Basic Information
Gallinacin-10 (Gal-10) (Beta-defensin 10) (Gallinacin-8) (Gal-8)
Antimicrobial
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
68 amino acids
C319H502N84O85S8
Standard
Sequence
MKILCLLFAVLLFLFQAAPGSADPLFPDTVACRTQGNFCRAGACPPTFTISGQCHGGLLNCCAKIPAQ
Physicochemical Analysis
7130.43 Da
8.24
1.52
1.15
0.0223
0.65
0.56
0.28
34.66
90.59
0.0882
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2619.32
-24.51
93.0
96.0
221.0
496.0
13.0
73.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0101054 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Beta-defensin; Defensin
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Non-hemolytic Antibacterial Antifungal
Streptococcus bovis ATCC 49147
50±0.0 μg/mL
MIC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID15148642;15310403;17244739; 25941665 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15148642/
RECORD: Rec_0431789 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibacterial Defensin
Streptococcus bovis ATCC 49147
100±0.58 μg/mL
MBC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID25941665
RECORD: Rec_0431790 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibacterial Defensin
Staphylococcus epidermidis ATCC 12228
50±0.0 μg/mL
MIC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID25941665
RECORD: Rec_0431791 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibacterial Defensin
Staphylococcus epidermidis ATCC 12228
100±0.58 μg/mL
MBC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID25941665
RECORD: Rec_0431792 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial Antibacterial Defensin
Staphylococcus aureus MRSA ATCC 43330
50±1.3 μg/mL
MIC
PaperAntimicrobial activity of chicken AvBD-10 against pathogenic microorganisms. Front Cell Infect Microbiol. 2015;5:36. PMID:25941665. DOI:10.3389/fcimb.2015.00036. PMID25941665
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