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MYP_010011
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Basic Information
Dermaseptin-like PBN2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
70 amino acids
C338H555N85O108S2
Standard
Sequence
MAFLKKSLFLVLFLALVPLSICEEKKSEEENEEKQEDDQSEEKRGLVTSLIKGAGKLLGGLFGSVTGGQS
Physicochemical Analysis
7601.66 Da
4.88
-3.49
-3.75
-0.0498
-0.16
0.59
0.04
60.65
98.86
0.0571
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3134.52
-29.34
107.0
107.0
272.0
533.0
5.0
73.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0120628 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID18929530 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18929530/
RECORD: Rec_0352014 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID18929530 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18929530/
RECORD: Rec_0358188 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID18929530 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18929530/
RECORD: Rec_0401428 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin; Plasticin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Cytolytic Cytotoxic Hemolytic Synergistic peptide
Escherichia coli (Gram-negative)
PaperA consistent nomenclature of antimicrobial peptides isolated from frogs of the subfamily Phyllomedusinae PMID12709067;15222751;17128968;18644413;25291467 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12709067/