Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length140 amino acids

Chemical FormulaC690H1084N184O185S16

DescriptionStandard

        MVWLISSPQSWLRSSCILGTTGPLTPPWASCCPRSCLDLQPNKCWAPSSRAQLAWFLFSCVLPSSPSPDLVAMTQLLLLIVALLVLGHVPPGRSEFKRCWKGQGACRPYCTRHEAYMQLCPDASLCCLAYGLKMAKTENV
    

Molecular Weight15430.15 Da

Isoelectric Point (pI)8.79

Net Charge (pH 7.0)5.56

Net Charge (pH 7.4) 5.05

Charge Density (pH 7.0) 0.0397

GRAVY Index0.22

Hydrophobic Moment 0.55

Boman Index0.15

Instability Index87.81

Aliphatic Index 89.21

Aromaticity 0.0857

Extinction Coeff. Reduced 37470.00

Extinction Coeff. Oxidized 38220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5754.70

LogP -50.75

H-bond Donors 211.0

H-bond Acceptors 209.0

Rotatable Bonds 478.0

Heavy Atoms 1075.0

Ring Count 34.0

Amide Bonds 147.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0208619 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence