Peptide Database

Peptide NameTPC1 (C-terminally truncated CSP)

Function Ontology

Antimicrobial ▸ Quorum sensing modulation

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC102H154N28O29

DescriptionStandard

        SGSLSTFFRLFNRSFTQALG
    

Molecular Weight2236.48 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)1.46

Net Charge (pH 7.4) 1.25

Charge Density (pH 7.0) 0.0730

GRAVY Index0.15

Hydrophobic Moment 0.79

Boman Index0.10

Instability Index33.87

Aliphatic Index 63.50

Aromaticity 0.2000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 947.58

LogP -11.60

H-bond Donors 35.0

H-bond Acceptors 31.0

Rotatable Bonds 72.0

Heavy Atoms 159.0

Ring Count 4.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0157169 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Quorum-sensing agonist Cell-cell communication Quorum sensing

TargetStreptococcus mutans quorum-sensing (ComD/ComE) system

Activity29 nM

MethodAC50; quorum-sensing activation (lacZ reporter) assay