Peptide Database

Peptide NameAntimicrobial peptide 1 (MJ-AMP1) (AMP1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC294H459N79O78S8

DescriptionStandard

        LPVAFLKFAIVLILFIAMSAMIEAQCIGNGGRCNENVGPPYCCSGFCLRQPGQGYGYCKNR
    

Molecular Weight6604.79 Da

Isoelectric Point (pI)8.65

Net Charge (pH 7.0)2.70

Net Charge (pH 7.4) 2.40

Charge Density (pH 7.0) 0.0443

GRAVY Index0.41

Hydrophobic Moment 0.48

Boman Index0.22

Instability Index38.08

Aliphatic Index 86.39

Aromaticity 0.1148

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2489.28

LogP -21.95

H-bond Donors 89.0

H-bond Acceptors 89.0

Rotatable Bonds 211.0

Heavy Atoms 459.0

Ring Count 11.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0335810 VERIFIED: YES

Provenance & Taxonomy

OrganismMirabilis jalapa [other]

FamilyAMP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Defense peptide Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria