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MYP_009880
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Standard
44 amino acids
C241H362N64O85S
Standard
Sequence
SLEQIWNNMTWEEWDREINNYTELIHELIEESQNQQEKNEQELL
Physicochemical Analysis
5547.90 Da
4.05
-10.42
-10.70
-0.2369
-1.37
0.64
-0.20
66.74
79.77
0.0909
17990.00
17990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2501.33
-22.80
81.0
77.0
192.0
391.0
8.0
54.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0106496 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Evidence URLhttps://patents.google.com/patent/US7575750B2/en PatentUS 7575750 B2
RECORD: Rec_0419406 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
HIV gp41 fusion inhibitor
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Anti-HIV Fusion inhibitor
HIV-1
0.00093 μM
IC50
PaperHIV fusion inhibitor peptide T-1249 is able to insert or adsorb to lipidic bilayers. Putative correlation with improved efficiency; Patent: Human immunodeficiency virus (HIV) gp41 peptide derivatives with enhanced solubility and antiviral activity PMID15535700 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15535700/ PatentUS 7575750 B2