Peptide Database

Peptide Namegamma-gliadin 1380 (p111-p130; E115) ; gamma-gliadin M12 M36999 (111-130) homologous to DQ2-gamma-IV

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC68H95N17O20

DescriptionStandard

        FPQPEQQFPQPQ
    

Molecular Weight1470.58 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.1031

GRAVY Index-1.82

Hydrophobic Moment 0.41

Boman Index-0.18

Instability Index161.82

Aliphatic Index 0.00

Aromaticity 0.1667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 601.01

LogP -5.57

H-bond Donors 15.0

H-bond Acceptors 19.0

Rotatable Bonds 41.0

Heavy Atoms 105.0

Ring Count 6.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0279298 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E115; Reported substitutions/positions: M12; Reported substitutions/positions: M36999

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay