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MYP_009781
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Basic Information
Ixosin-B (Ticks, Arthropods, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
32 amino acids
C165H262N56O49
Standard
Sequence
QLKVDLWGTRSGIQPEQHSSGKSDVRRWRSRY
Physicochemical Analysis
3814.19 Da
10.88
3.85
3.59
0.1203
-1.39
0.49
-0.41
86.30
54.69
0.0938
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1761.21
-20.83
65.0
54.0
128.0
270.0
7.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0186405 VERIFIED: YES
Provenance & Taxonomy
I. sinensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
100 μM
MIC
PMID23570790 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23570790/
RECORD: Rec_0188120 VERIFIED: YES
Provenance & Taxonomy
Ixodes sinensis [Animal]
Ixosin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperComp Biochem Physiol B Biochem Mol Biol. 2008;149(4):557-61. | http://www.ncbi.nlm.nih.gov/pubmed/18295522 PMID18295522 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18295522/
RECORD: Rec_0200325 VERIFIED: YES
Provenance & Taxonomy
Ixodes sinensis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus
2.5 μg/mL
MIC
PMID18295522 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18295522/
RECORD: Rec_0202753 VERIFIED: YES
Provenance & Taxonomy
Ixodes sinensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PMID18295522 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18295522/
RECORD: Rec_0212123 VERIFIED: YES
Provenance & Taxonomy
Ixodes sinensis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans
7.5 μg/mL
MIC
PMID18295522 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18295522/
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