Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC418H669N115O123S14

DescriptionStandard

        MKTFSVAVVAAVLLALICLQESSALPLSEVDDVEVPVMDDNGAAVYEEMPVDSWKMPYTNRHKRSPKRCKFCCNCCPGMRGCGVCCRF
    

Molecular Weight9722.39 Da

Isoelectric Point (pI)6.52

Net Charge (pH 7.0)-0.49

Net Charge (pH 7.4) -0.91

Charge Density (pH 7.0) -0.0056

GRAVY Index0.13

Hydrophobic Moment 0.61

Boman Index0.05

Instability Index66.11

Aliphatic Index 75.23

Aromaticity 0.0682

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3774.01

LogP -36.47

H-bond Donors 138.0

H-bond Acceptors 138.0

Rotatable Bonds 314.0

Heavy Atoms 670.0

Ring Count 14.0

Amide Bonds 91.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0347621 VERIFIED: NO

Provenance & Taxonomy

OrganismTakifugu flavidus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal