Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length129 amino acids

Chemical FormulaC644H998N148O201S5

DescriptionStandard

        MLYLAVSEYSFQTTAFAYYTAGAFNIIITDEVCSYFNITTETFGSIIPEVAQYYAESQPVMLNLTATKTPVISLQTDAFTIEIHGSMEVLAVLPDATTQSLFTVNITTNSSISLTLFDQKLIGSLCLNR
    

Molecular Weight14190.01 Da

Isoelectric Point (pI)4.09

Net Charge (pH 7.0)-8.42

Net Charge (pH 7.4) -8.74

Charge Density (pH 7.0) -0.0652

GRAVY Index0.42

Hydrophobic Moment 0.49

Boman Index0.27

Instability Index47.95

Aliphatic Index 102.09

Aromaticity 0.1163

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10555.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5571.47

LogP -53.63

H-bond Donors 194.0

H-bond Acceptors 199.0

Rotatable Bonds 455.0

Heavy Atoms 998.0

Ring Count 20.0

Amide Bonds 140.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0262533 VERIFIED: NO

Provenance & Taxonomy

OrganismCrocodylus porosus (Saltwater crocodile) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria