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MYP_009743
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Basic Information
B-GR23
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
23 amino acids
C106H185N31O29
Standard
Sequence
GVTFNALKGVAKTVAAQLLKTAR
Physicochemical Analysis
2357.79 Da
11.26
3.76
3.55
0.1634
0.42
0.57
0.12
0.17
110.43
0.0435
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
990.35
-10.29
35.0
33.0
80.0
166.0
1.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0184467 VERIFIED: YES
Provenance & Taxonomy
Hylarana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
16 μM
MIC
PaperBrevinin-GR23 from frog Hylarana guentheri with antimicrobial and antibiofilm activities against Staphylococcus aureus
RECORD: Rec_0186231 VERIFIED: YES
Provenance & Taxonomy
Hylarana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Anti-Gram-positive Hemolytic
PMID31549575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31549575/
RECORD: Rec_0230143 VERIFIED: YES
Provenance & Taxonomy
Hylarana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Anti-Gram-positive
Escherichia coli
64 μM
MIC
PMID31549575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31549575/
RECORD: Rec_0252281 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
64 μM
MIC
PMID31549575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31549575/
RECORD: Rec_0321158 VERIFIED: YES
Provenance & Taxonomy
Hylarana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Anti-Gram-positive
Streptococcus mutans
100 μM
MIC
PMID31549575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31549575/
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