Peptide Database

Peptide NameKlebicin B

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length720 amino acids

Chemical FormulaC3241H5228N964O1054S14

DescriptionStandard

        MADIRGQIHTVSSEEGSTTVSGFDGVRSSSTGNGGSQGGQGPQGQSLVMHNGQMGYWENRSSGAGNNEHTTRAFVAVGPSEAEKAARAEKVAKEKQQAEEAAKAFAAKTAAASAAAEKERQNAISAAAAAGQHQTVPDARNNLNQATAEASRLKTVADNALNTAKNKRKEAIDAVPVATQAEKKYQDLQQSIKGLTLNNNGQYGTQKWEVISSNKEHDHWGYRFYPSGITKAQVDAAQNDAVNKRNAATSLASQATAAEQASLQASAAYNAAETRRQAAQAALASAEQAAAAERKRQEAEAAAAAAAEKKRQADAAAKAAEEARAIAEKAKALQARCTAADKLKSSEIQAVRGIPATAAPFAIPLTWSTASRGGFTLSADAAASLGAFISEALATLSIAVVANPVALTIVGLVLSKSVGVGSDMVPGRDISSMMPGDAFGLPDTAALNKAADQKTSVSMPVRGRLVMNDSGILDVQLVKTNTAGAVKVARAVLDKETGYWGYTLPAVADVPAQTIFVSPADALGANGPLTLSGPVPLPERILHTGDQISAPQATDKTVTPVADDLDFDDIILVFPPESGLKPLYVMYRSPRNMPGTVSGKGQNVGNNWMGGASTGDGAPVPSQIADKLRGKTFGSFDSTRRAFWKAVADDSALSKQFSEADINQMKAGRAPTADFLESVGKRVKIELHHEKEISQGGAVMDVDNIKALTPKNHIETHKGK
    

Molecular Weight75010.92 Da

Isoelectric Point (pI)8.52

Net Charge (pH 7.0)3.54

Net Charge (pH 7.4) 2.58

Charge Density (pH 7.0) 0.0049

GRAVY Index-0.36

Hydrophobic Moment 0.63

Boman Index-0.01

Instability Index37.87

Aliphatic Index 74.24

Aromaticity 0.0458

Extinction Coeff. Reduced 53400.00

Extinction Coeff. Oxidized 53400.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024367 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyColicin/Pyocin

Tax ID573

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli

MethodQualitative functional evidence