Peptide Database

Peptide NameEsculentin-2LF1 antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC371H611N99O110S5

DescriptionStandard

        MFTLKKSMLLLFFLGTISLSLCEEERSADEDDGEKEVKRGIFSLIKTAAKFVGKNLLKQAGKAGLEHLACKANNQC
    

Molecular Weight8378.74 Da

Isoelectric Point (pI)8.50

Net Charge (pH 7.0)1.57

Net Charge (pH 7.4) 1.23

Charge Density (pH 7.0) 0.0207

GRAVY Index-0.09

Hydrophobic Moment 0.71

Boman Index0.01

Instability Index24.43

Aliphatic Index 93.82

Aromaticity 0.0658

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3408.79

LogP -31.28

H-bond Donors 120.0

H-bond Acceptors 118.0

Rotatable Bonds 299.0

Heavy Atoms 585.0

Ring Count 6.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024266 VERIFIED: NO

Provenance & Taxonomy

OrganismAmolops lifanensis [Animal]

Tax ID325558

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal