Peptide Database

Peptide NameDEFA1B isoform 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC445H707N127O132S8

DescriptionStandard

        MRTLAILAAILLVALQAQAEPLQARGDEFAAAQEQIPADNPEVVVSLAWDESLAPKDSGSRKNMACACRIPSCIAGERRYGTCFYQGRVWAFCC
    

Molecular Weight10204.67 Da

Isoelectric Point (pI)5.28

Net Charge (pH 7.0)-1.54

Net Charge (pH 7.4) -1.86

Charge Density (pH 7.0) -0.0164

GRAVY Index0.10

Hydrophobic Moment 0.48

Boman Index0.07

Instability Index56.37

Aliphatic Index 87.45

Aromaticity 0.0745

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4142.38

LogP -41.20

H-bond Donors 148.0

H-bond Acceptors 139.0

Rotatable Bonds 330.0

Heavy Atoms 712.0

Ring Count 14.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409274 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Bacterium]

FamilyDefensin

Tax ID9601

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence