Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC366H575N103O111S11

DescriptionStandard

        MEKKSLAGLCFLFLVLFVAQECVLQTEAKTCENLADTYRGPCFTTGSCDDHCKNKEHLLSGRCRDDFRCWCTKNC
    

Molecular Weight8546.82 Da

Isoelectric Point (pI)6.68

Net Charge (pH 7.0)-0.41

Net Charge (pH 7.4) -0.90

Charge Density (pH 7.0) -0.0055

GRAVY Index-0.23

Hydrophobic Moment 0.56

Boman Index-0.07

Instability Index30.72

Aliphatic Index 63.73

Aromaticity 0.0933

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3475.55

LogP -36.42

H-bond Donors 131.0

H-bond Acceptors 124.0

Rotatable Bonds 286.0

Heavy Atoms 591.0

Ring Count 11.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0194243 VERIFIED: NO

Provenance & Taxonomy

OrganismPhaseolus vulgaris [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence