Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC221H338N62O72S6

DescriptionStandard

        HPGDAQGPDSCNHGGGLCRVGTCVSGEYPAQYCFEPIILCCKNLPPATTE
    

Molecular Weight5207.81 Da

Isoelectric Point (pI)5.01

Net Charge (pH 7.0)-3.11

Net Charge (pH 7.4) -3.52

Charge Density (pH 7.0) -0.0622

GRAVY Index-0.26

Hydrophobic Moment 0.45

Boman Index0.10

Instability Index42.46

Aliphatic Index 56.60

Aromaticity 0.0600

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2082.23

LogP -25.79

H-bond Donors 73.0

H-bond Acceptors 77.0

Rotatable Bonds 157.0

Heavy Atoms 361.0

Ring Count 11.0

Amide Bonds 53.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344095 VERIFIED: YES

Provenance & Taxonomy

OrganismCyanistes caeruleus [Animal]

FamilyDefensin

Tax ID156563

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

PaperLocus-specific protocol for nine different innate immune genes (antimicrobial peptides: β-defensins) across passerine bird species reveals within-species coding variation and a case of trans-species polymorphisms [PMID:21676198] PMID21676198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21676198/

RECORD: Rec_0401933 VERIFIED: NO