Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC751H1188N228O217S6

DescriptionStandard

        MAKVQFTQRKETKAVFVHCSATKPSMDIGVREIRQWHKERGWLDIGYHFVIRRDGTIEEGREVGSVGAHVEGHNSTSVGICLVGGVDEYNRFKANFTPIQMQTLRGLLENLKGRYPNVAIRAHHDVAAKACPSFDLQRWLKTNELVTSDRG
    

Molecular Weight17075.25 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.10

Net Charge (pH 7.4) 4.45

Charge Density (pH 7.0) 0.0338

GRAVY Index-0.47

Hydrophobic Moment 0.75

Boman Index-0.08

Instability Index30.04

Aliphatic Index 77.42

Aromaticity 0.0795

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7215.72

LogP -73.80

H-bond Donors 257.0

H-bond Acceptors 235.0

Rotatable Bonds 573.0

Heavy Atoms 1202.0

Ring Count 26.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0180590 VERIFIED: NO

Provenance & Taxonomy

OrganismPectobacterium phage DU_PP_II [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic