Peptide Database

Peptide NamePV, pEM-2 (1-11)+Mastoparan-M (10-14)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC99H158N26O16

DescriptionStandard

        KKWRWWLKALAKKLL
    

Molecular Weight1968.48 Da

Isoelectric Point (pI)11.39

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.3837

GRAVY Index-0.53

Hydrophobic Moment 0.56

Boman Index-0.14

Instability Index44.43

Aliphatic Index 117.33

Aromaticity 0.2000

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 710.09

LogP 1.49

H-bond Donors 27.0

H-bond Acceptors 22.0

Rotatable Bonds 67.0

Heavy Atoms 141.0

Ring Count 6.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418790 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetAcinetobacter baumannii isolates

Activity0.4±0.1 μg/mL

MethodMIC

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