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MYP_009490
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Basic Information
PV, pEM-2 (1-11)+Mastoparan-M (10-14)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
15 amino acids
C99H158N26O16
Standard
Sequence
KKWRWWLKALAKKLL
Physicochemical Analysis
1968.48 Da
11.39
5.76
5.54
0.3837
-0.53
0.56
-0.14
44.43
117.33
0.2000
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
710.09
1.49
27.0
22.0
67.0
141.0
6.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0015770 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii
0.5
MBC
PMID27591703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0022234 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
sheep red blood cells
PMID27591703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0048304 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-positive bacteria: Staphylococcus aureus isolates
0.5±0.0 μg/mL
MIC
PMID27591703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0060999 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
5 % hemolysis at 8 μg/mL
Hemolysis
PMID27591703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0071405 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii
0.4
MIC
PMID27591703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
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